Sunday, February 18, 2018

Targeting Specific Chemical Compounds?

SBC's Natural Product Library holds more than 40,000 extracts (plants and microbes) derived from the Sarawak rainforest for discovery screening through agreements and collaborations.

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Therapeutic Potential of the Translation Inhibitor Silvestrol in Hepatocellular Cancer
Kogure, T., Kinghorn, A. D., Yan, I., Bolon, B., Lucas, D. M., Grever, M. R., & Patel, T. (2013).
PloS One, 8(9), e76136. doi:10.1371/journal.pone.0076136. eCollection 2013


Targeted cancer therapy: what if the driver is just a messenger?
Schatz, J. H., & Wendel, H.-G. (2011).
Cell Cycle (Georgetown, Tex.), 10(22), 3830–3. doi:10.4161/cc.10.22.18288. Epub 2011 Nov 15.

The relevance of higher plants in lead compound discovery programs.
Kinghorn, a D., Pan, L., Fletcher, J. N., & Chai, H. (2011).
Journal of Natural Products, 74(6), 1539–55. doi:10.1021/np200391c. Review

Potential of plant-derived natural products in the treatment of leukemia and lymphoma.
Lucas, D. M., Still, P. C., Pérez, L. B., Grever, M. R., & Kinghorn, A. D. (2010).
Current Drug Targets, 11(7), 812–22. Review.

Silvestrol: An emerging compound for cancer therapy.
Yeo, T.C.
Biodiversity-Biotechnology: Gateway to Discoveries, Sustainable Utilization and Wealth Creation, Manurung, R., Zaliha, C.A., Fasihuddin, B.A. and Kuek, C. (Eds), 19-21 November 2008, Kuching, Sarawak, Malaysia. pp229-33.

For purchase of silvestrol as reagent for studying molecular pathways, please contact us through the following form:

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Date updated: 12 February 2018.